How does antibiotic resistance develop? 

Development of resistance is a natural phenomenon that has existed since time immemorial. Resistance can result from changes in the bacterium’s own genome or if resistant genes are received from other bacteria.

Compared with non-resistant bacteria, resistant bacteria are more likely to have difficulty establishing themselves under normal circumstances because they are less robust. Wherever antibiotics are used, however, resistant bacteria gain a survival advantage over non-resistant microbes. They are able to survive and replicate themselves. The increased use of antibiotics in human and veterinary medicine has accelerated the spread of antibiotic resistance.

What are antibiotics?

Antibiotics are medicines that kill bacteria or inhibit their growth. This makes them an important medical weapon in the fight […]
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Antibiotics are medicines that kill bacteria or inhibit their growth. This makes them an important medical weapon in the fight against bacterial diseases in both humans and animals. Antibiotics are used against bacterial infections such as blood poisoning or pneumonia. If the immune system is weakened, antibiotics can also be prescribed as a preventive measure to protect against infections.

There are different classes of antibiotics with different mechanisms of action. Each class of antibiotics attacks bacteria in a different way. Some prevent bacteria from synthesising new cell walls, while others block the transmission of genetic information during replication. Bacteria can get used to antibiotics and become resistant, i.e. insensitive, to antibiotics. That’s how antibiotics lose their effectiveness.

When are antibiotics effective? And when not?

Antibiotics are prescription-only drugs that prevent the growth of bacteria or kill them. Antibiotics only work against bacteria. They are […]
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Antibiotics are prescription-only drugs that prevent the growth of bacteria or kill them. Antibiotics only work against bacteria. They are useless against viruses, fungi and parasites, which can cause many different diseases in humans and animals. This makes it important for antibiotics to be prescribed for bacterial infections only.

What is antibiotic resistance?

Antibiotic resistance means that bacteria are unaffected by antibiotics. Bacteria have the ability to adapt quickly to their environment…
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Antibiotic resistance means that bacteria are unaffected by antibiotics. Bacteria have the ability to adapt quickly to their environment. Although this is a natural process, it also means they can get used to antibiotics and become resistant to them. The antibiotics then lose their effectiveness as a medicine. This unwanted adaptation process is helped and speeded up if antibiotics are used too often or wrongly.

So it is not people or animals that become resistant to antibiotics, but the bacteria. The resistant microbes are able to multiply very rapidly and can actually pass the resistance on to other bacteria. Since bacteria occur almost everywhere, they are easily transferred from one human being to another, or from an animal to a human and vice versa. If resistant bacteria cause a disease in humans or animals, it can be difficult or impossible to treat. In the worst-case scenario, it may even lead to death.

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Why are resistant bacteria a problem?

Antibiotics are an important pillar of modern medicine. If they lose their effectiveness, there are far-reaching consequences…
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Antibiotics are an important pillar of modern medicine. If they lose their effectiveness, there are far-reaching consequences for humans and animals. For example, bacterial infections involving resistant microbes take longer to treat or may be untreatable in certain cases.

Resistance can cause higher costs in human and veterinary medicine as well as agriculture, and may make the disease more acute or even result in death. People or animals that have never had antibiotics in their life can also fall victim to an infection with resistant bacteria. The sharp increase we are seeing in antibiotic resistance worldwide is a very worrying phenomenon.

Bacteria know no boundaries

Numerous bacteria can be transmitted between humans, animals and the environment, including resistant microbes. This means that antibiotic-resistant bacteria are […]
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Numerous bacteria can be transmitted between humans, animals and the environment, including resistant microbes. This means that antibiotic-resistant bacteria are of concern to everyone – whether or not an individual person or animal has ever been treated before with antibiotics.

Coordinated action against antibiotic resistance

The effectiveness of antibiotics can only be maintained if the human, animal, agricultural and environmental sectors all work together to […]
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The effectiveness of antibiotics can only be maintained if the human, animal, agricultural and environmental sectors all work together to combat antibiotic resistance. Since resistant bacteria can be exchanged between humans, animals and the environment, it is essential that any measures taken are coordinated with all stakeholders at the same time. For this reason, representatives of four Swiss federal agencies – the Federal Office of Public Health (FOPH), Federal Food Safety and Veterinary Office (FSVO), Federal Office for Agriculture (FOAG) and the Federal Office for the Environment (FOEN) – are in close contact with each other and exchange information on a regular basis. All agencies work hand-in-hand to ensure that the Strategy on Antibiotic Resistance (StAR) is implemented in a comprehensive and coordinated manner. International networking and the exchange of knowledge must also be supported, because antibiotic resistance is a global problem…find out more